Principal Investigator
Jonathan LoTempio Jr
Faculty in computational genomics and bioethics at UC Irvine, with expertise in pangenome reference systems, rare disease genomics, and governance of data- and AI-driven biomedical research.
Areas of expertise
- Human genome informatics and pangenomes (graph genomes)
- Rare disease genomics, reanalysis, and learning health systems
- Bioethics and ELSI in genomics (consent, governance, benefit sharing)
- Data privacy, commercialization, and stewardship of genomic data
- Benchmarking and evaluation of AI-enabled biomedical tools
- Conversational AI for informed consent and research engagement
Topics frequently requested by media
- Consumer genetics and 23andMe
- DNA data in bankruptcy and M&A
- Genomic privacy and consent
- Rare disease diagnosis and reanalysis
- Pangenomes and reference bias
- Evaluation of genomic AI
- Chatbots for informed consent
- Auditable AI in health research
- Bioethics of data sharing
Background
- PhD in Genomics and Bioinformatics
- Training at the National Human Genome Research Institute (NIH)
- Fulbright Schuman fellowship (EU)
- NIH Ruth L. Kirschstein fellowship in bioethics (University of Pennsylvania)
- Leads a lab spanning genome informatics and embedded bioethics
Media inquiries
For press inquiries or requests for expert comment, contact .